The 2 designs are a special category of the factorial experiments where all the factors are at two levels. The fact that these designs contain factors at only two levels and are orthogonal greatly simplifies their analysis even when the number of factors is large. The use of 2 designs in investigating a large number of factors calls for a revision of the notation used previously for the ANOVA models. The case for revised notation is made stronger by the fact that the ANOVA and multiple linear regression models are identical for 2 designs because all factors are only at two levels. Therefore, the notation of the regression models is applied to the ANOVA models for these designs, as explained below.
This section contains the following subsections:
Based on the notation of Chapter
6, the ANOVA model for a two level factorial experiment with three
factors would be as follows:
(1)where:
represents the overall mean.
represents the independent effect of the first factor (factor ) out of the two effects and .
represents the independent effect of the second factor (factor ) out of the two effects and .
represents the independent effect of the interaction out of the other interaction effects.
represents the effect of the third factor (factor ) out of the two effects and .
represents the effect of the interaction out of the other interaction effects.
represents the effect of the interaction out of the other interaction effects.
represents the effect of the interaction out of the other interaction effects .
is the random error term.
The notation for a linear regression model having three predictor variables
with interactions is:
(2)
The notation for the regression model is much more convenient, especially for the case when a large number of higher order interactions are present. [Note] In two level experiments, the ANOVA model requires only one indicator variable to represent each factor for both qualitative and quantitative factors. Therefore, the notation for the multiple linear regression model can be applied to the ANOVA model of the experiment that has all the factors at two levels. For example, for the experiment of Eqn. (1), can represent the overall mean instead of , and can represent the independent effect, , of factor . Other main effects can be represented in a similar manner. The notation for the interaction effects is much more simplified, e.g. can be used to represent the three factor interaction effect, .
As mentioned earlier, it is important to note that the coding for the indicator variables for the ANOVA models of two level factorial experiments is reversed from the coding followed in the Chapter 6, Analysis of Experiments. Here represents the first level of the factor while represents the second level. This is because for a two level factor a single variable is needed to represent the factor for both qualitative and quantitative factors. [Note] For quantitative factors, using for the first level (which is the low level) and 1 for the second level (which is the high level) keeps the coding consistent with the numerical value of the factors. [Note] The change in coding between the two coding schemes does not affect the analysis except that signs of the estimated effect coefficients will be reversed (i.e. numerical values of , obtained based on the coding of Chapter 6, and , obtained based on the new coding, will be the same but their signs would be opposite).


In summary, the ANOVA model for the experiments with all factors at two levels is different from the ANOVA models for other experiments in terms of the notation in the following two ways:
Consider the design matrix, , for the 2 design shown in Figure 7.3 (b). The () matrix is:

Notice that, due to the orthogonal design of the matrix, the has been simplified to a diagonal
matrix which can be written as:
where represents the identity matrix of the
same order as the design matrix, . Since there are eight observations
per replicate of the 2 design, the ' matrix for replicates of this design can be written
as:
The matrix for any 2 design can now be written as:
(3)
Then the variance-covariance matrix for the 2 design is:
(4, 5)
Note that the variance-covariance matrix for the 2 design is also a diagonal matrix. Therefore, the estimated effect coefficients (, , etc.) for these designs are uncorrelated. This implies that the terms in the 2 design (main effects, interactions) are independent of each other. Consequently, the extra sum of squares for each of the terms in these designs is independent of the sequence of terms in the model, and also independent of the presence of other terms in the model. As a result the sequential and partial sum of squares for the terms are identical for these designs and will always add up to the model sum of squares. Multicollinearity is also not an issue for these designs. [Note]
It can also be noted from Eqn. (5), that in addition
to the matrix being diagonal, all diagonal
elements of the matrix are identical. This means that
the variance (or its square root, the standard error) of all estimated
effect coefficients are the same. The standard error, , for all the coefficients is:
(6)
This property is used to construct the normal probability plot of effects in 2 designs and identify significant effects using graphical techniques. [Note] For details on the normal probability plot of effects in DOE++, refer to Chapter 7, Normal Probability Plot of Effects.
To illustrate the analysis of a full factorial 2 design, consider a three factor experiment to investigate the effect of honing pressure, number of strokes and cycle time on the surface finish of automobile brake drums. Each of these factors is investigated at two levels. The honing pressure is investigated at levels of 200 and 400 , the number of strokes used is 3 and 5 and the two levels of the cycle time are 3 and 5 seconds. The design for this experiment is set up in DOE++ as shown in Figures 7.5 and 7.6 . It is decided to run two replicates for this experiment. The surface finish data collected from each run (using randomization) and the complete design is shown in Figure 7.7. The analysis of the experiment data is explained next.
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Figure 7.5: Design properties for the experiment in Example 7.1. |
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Figure 7.6: Factor properties for the experiment in Example 7.1. |
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Figure: 7.7: Experiment design for Example 7.1 to investigate the surface finish of automobile brake drums. |
The applicable ANOVA model using the notation for 2 designs is:
(7)where the indicator variable, represents factor (honing pressure), represents the low level of 200 and represents the high level of 400 . Similarly, and represent factors (number of strokes) and (cycle time), respectively. is the overall mean, while , and are the effect coefficients for the
main effects of factors , and , respectively. , and are the effect coefficients for the
, and interactions, while represents the interaction.
If the subscripts for the run (; 1 to 8) and replicates (; 1,2) are included, then the model
can be written as:
(8)
To investigate how the given factors affect the response, the following hypothesis tests need to be carried:
This test investigates the main effect of factor (honing pressure). The statistic for
this test is:
where is the mean square for factor and is the error mean square. Hypotheses
for the other main effects, and , can be written in a similar manner.
This test investigates the two factor interaction . The statistic for this test is:
where is the mean square for the interaction
and is the error mean square. Hypotheses
for the other two factor interactions, and , can be written in a similar manner.
This test investigates the three factor interaction . The statistic for this test is:
where is the mean square for the interaction
and is the error mean square.
To calculate the test statistics, it is convenient to express the ANOVA model of Eqn. (7) in the form .
In matrix notation, the ANOVA model of Eqn. (7)
can be expressed as: [Note]
where:

Knowing the matrices , and , the extra sum of squares for the
factors can be calculated. [Note]
These are used to calculate the mean squares that are used to obtain the
test statistics. Since the experiment design is orthogonal, the partial
and sequential extra sum of squares are identical. The extra sum of squares
for each effect can be calculated as shown next. As an example, the extra
sum of squares for the main effect of factor is:
where is the hat matrix and is the matrix of ones. The matrix
can be calculated using where is the design matrix, , excluding the second column that
represents the main effect of factor . Thus, the sum of squares for the
main effect of factor is:
Similarly, the extra sum of squares for the interaction effect is:
The extra sum of squares for other effects can be obtained in a similar manner.
Knowing the extra sum of squares, the test statistic for the effects
can be calculated. For example, the test statistic for the interaction
is:
where is the mean square for the interaction and is the error mean square. [Note]
The value corresponding to the statistic,
, based on the distribution with one degree of freedom
in the numerator and eight degrees of freedom in the denominator is: [Note]

Assuming that the desired significance is 0.1, since value > 0.1, it can be concluded that the interaction between honing pressure and number of strokes does not affect the surface finish of the brake drums. Tests for other effects can be carried out in a similar manner. The results are shown in the ANOVA Table in Figure 7.8. The values S, R-sq and R-sq(adj) in the figure indicate how well the model fits the data. The value of S represents the standard error of the model, R-sq represents the coefficient of multiple determination and R-sq(adj) represents the adjusted coefficient of multiple determination. For details on these values refer to Chapter 5, Multiple Linear Regression Analysis.
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Figure 7.8: ANOVA table for the experiment in Example 7.1. |
The estimate of effect coefficients can also be obtained:
The coefficients and related results are shown in the Regression Information Table in Figure 7.9. In the table, the Effect column displays the effects, which are simply twice the coefficients. The Standard Error column displays the standard error, . The Low CI and High CI columns display the confidence interval on the coefficients. The interval shown is the 90% interval as the significance is chosen as 0.1. The T Value column displays the statistic, , corresponding to the coefficients. The P Value column displays the value corresponding to the statistic. (For details on how these results are calculated, refer to Chapter 6, Analysis of Experiments.) Plots of residuals can also be obtained from DOE++ to ensure that the assumptions related to the ANOVA model of Eqn. (7) are not violated.
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Figure 7.9: Regression Information table for the experiment in Example 7.1. |
Model Equation
From the analysis results in Figure 7.8, it is
seen that effects , and are significant. In DOE++, the values for the significant effects
are displayed in red in the ANOVA Table for easy identification. Using
the values of the estimated effect coefficients, the model for the present
2 design in terms of the coded values
can be written as:
To make the model hierarchical, the main effect, , needs to be included in the model
(because the interaction is included in the model). [Note]
The resulting model is:
This equation can be viewed in DOE++, as shown in Figure 7.10, using the Show Analysis Summary icon in the Control Panel. The equation shown in the figure will match the hierarchical model once the required terms are selected using the Select Effects icon.
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Figure 7.10: The model equation for the experiment of Example 7.1. |
See Also:
Two Level Factorial Experiments
Multiple Linear Regression Analysis
Normal Probability Plot of Effects